Inadequate antiprotease activity in the lungs due to alpha-1-antitrypsin (A1AT) deficiency is a factor of early-onset emphysema. We propose a new approach to gene therapy that involves the ...

Alpha-1-antitrypsin is a so-called protease inhibitor, a type of enzyme inhibitor. It is produced in the liver but exerts its effects in the lungs, where it regulates immune cell activity. This ...

Researchers at the University of Oulu have identified alpha-1 antitrypsin as a potential target for preventing spontaneous preterm birth. In a large genetic study of more than 200,000 mothers, a ...

Researchers at the University of Oulu have identified alpha-1 antitrypsin as a potential target for preventing spontaneous preterm birth. In a large ...

The two most common inherited liver diseases are hemochromatosis and alpha-1 antitrypsin deficiency. Hemochromatosis is a disease in which deposits of iron collect in the liver and other organs. The ...

Alpha-1 antitrypsin deficiency (AATD) is a genetic disease wherein the individual has a greater risk of developing chronic obstructive pulmonary disease (COPD), liver disease, and skin problems such ...

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Please provide your email address to receive an email when new articles are posted on . Direct-to-consumer testing, combined with clinical follow-up, helped identify patients with undiagnosed alpha-1 ...

Researchers examined the medical costs for patients with a rare subset of chronic obstructive pulmonary disease (COPD) caused by a deficiency in alpha-1 antitrypsin receiving augmentation therapy.

Researchers at the University of Oulu have identified alpha-1 antitrypsin as a potential target for preventing spontaneous preterm birth. In a large genetic study of more than 200,000 mothers, a ...

Alpha-1 antitrypsin deficiency is an inherited disorder that mostly affects the lung and liver. The condition occurs all over the world but its incidence differs according to regions and population.