Failure to remove proteinaceous cohesion, topological catenations, or to complete DNA replication by mitosis in the budding yeast S. cerevisiae causes sister chromatid nondisjunction and the formation ...

The amount of smoke in just one or two puffs of a cigarette can cause breaks in DNA and defects to a cell's chromosomes, leading to irreversible changes in genetic information being passed to a ...

Researchers at The University of Hong Kong (HKU) have made an exciting discovery about how human cells protect DNA during cell division, offering new insights into combating diseases such as cancer.

Chromosome missegregation in mitosis can result in aneuploidy, which is closely associated with tumorigenesis. During S phase and the metaphase–anaphase transition in mitosis, Topoisomerase IIα (Topo ...