Figure 1: The 16p telomeric region from a normal chromosome (16p13.3) and from the ZF-deleted chromosome (α− ZF 16p13.3). Figure 4: Transgenic mice expressing high levels of α-globin antisense RNA ...
Antisense transcripts are widespread and are found in all kingdoms of life. Their expression can be regulated either coordinately or independently of their neighbouring genes. Antisense transcripts ...
Dublin, Oct. 01, 2025 (GLOBE NEWSWIRE) -- The "Antisense Oligonucleotides Market Industry Trends and Global Forecasts to 2035: Distribution by Type of Antisense Molecule, Type of ASO Generation, ...
New York, USA, Aug. 28, 2025 (GLOBE NEWSWIRE) -- Antisense Oligonucleotide Therapeutics Clinical Trial Pipeline Appears Robust With 70+ Key Pharma Companies Actively Working in the Domain | ...
After a two-decade cycle of investor embrace and rejection, partnerships won and lost, failed clinical trials, layoffs, and rebuilds, Isis Pharmaceuticals has gained approval for the first ...
GSK is embarking on a journey with CAMP4 Therapeutics, paying $17.5 million upfront to collaborate on regulatory RNA-targeting therapeutics in neurodegenerative and kidney disease indications.
Many cognitive neurodevelopmental disorders are a result of too many or too few copies of certain genes or chromosomes. To date, no treatment options exist for this class of disorders. MECP2 ...
Almost two years ago, Julia Vitarello and Alek Makovec learned that their six-year-old daughter, Mila Makovec, has a rare, inherited neurodegenerative condition called Batten disease. The diagnosis ...
Biogen is still reeling from the pivotal failure of aducanumab in Alzheimer’s disease, but it is celebrating some positive news from another pipeline asset in neurology. Preliminary results from a ...
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Unexpected bacterial blocker: Antisense molecules inhibit oral Fusobacterium species linked to cancer progression
Fusobacteria, which are part of the oral microbiome, are suspected of playing a role in cancer progression. Scientists at the Helmholtz Institute for RNA-based Infection Research (HIRI) are working on ...
Patient 1 was a 24-year-old woman with type 1 hereditary angioedema and frequent breakthrough attacks. The attacks started when she was 13 years of age, and the frequency of attacks increased after ...
The pollen tube (PT) containing male gametes elongates and penetrates into the pistils for successful fertilization. However, the molecular mechanisms of plant fertilization remain largely unknown. We ...
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