A team of researchers from The University of Hong Kong (HKU) has made a significant breakthrough in understanding how energy metabolism and bone homeostasis are regulated in mice, which could lead to ...
Professor Changjun Li and his colleagues at Xiangya Hospital of Central South University have published a research paper titled "Mechanical protein polycystin-1 directly regulates osteoclastogenesis ...
A recent study identifies Neural EGFL-like 2 (NELL2), a secreted protein, as a key regulator of bone homeostasis, offering potential therapeutic applications for osteoporosis. NELL2 promotes ...
Although previous studies have implicated SIRT5 in mitochondrial metabolism and osteogenesis, its contribution to estrogen ...
Endothelial-to-Osteoblast Conversion (EC-to-OSB) regulates bone formation and homeostasis via the Kindlin-2/Piezo1/TGFβ/Runx2 axis. Reduced Kindlin-2 in endothelial ...
PC1, as a mechanical stress sensitive factor, influences osteoclastogenesis and bone resorption by regulating TAZ nuclear translocation. Patients with ADPKD, which is mainly caused by loss-of-function ...
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