Mating and meiosis -- the specialized cell division that reduces the number of chromosomes in a cell -- are related, but in most yeasts they are regulated separately. Not so in Candida lusitaniae, ...
Four hundred thirty-four patients with any invasive fungal infection from 24 enrolling PFN sites (15 US and 9 international) were entered, and 71% (307/434) of those patients completed 12 weeks of ...
For mating and meiosis, C. lusitaniae cells were grown on YPD medium (non-inducing) or PDA medium (inductive for mating/meiosis). RNA was isolated from cells using the Ribopure-Yeast Kit (Life ...
The last several decades have also produced an increased armamentarium of antifungal therapies for the treatment of candidemia. AmphotericinB deoxycholate, a polyene that acts by binding to ergosterol ...
PROVIDENCE, R.I. [Brown University] — From a biological point of view, the world's most exotic sex lives may be the ones lived by fungi. As a kingdom, they are full of surprises, and a new one ...
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