DNA is not randomly distributed within the nucleus but is packaged with proteins into chromatin, which is precisely folded ...

Immune cells are the elite athletes of the human body. While other cells stay in place, immune cells travel throughout our bodies, squeezing through small channels, stretching themselves, sampling the ...

New research shows the chromatin organizer Satb1 enables regulatory T cells to promote tumor growth while remaining ...

Human genomic DNA is wrapped around core histone proteins to form nucleosomes, the fundamental units of chromatin. During ...

A PLOS Genetics study shows that destabilizing chromatin through a histone H3 mutation hyperactivates the nutrient-sensing ...

Northwestern Medicine scientists have uncovered new details about the genetic structure of ovarian cancer stem cells, according to a study published in Advanced Science. Inside cells, DNA mixes with ...

Every cell in a body contains the same genetic sequence, yet each cell expresses only a subset of those genes. These cell-specific gene expression patterns, which ensure that a brain cell is different ...

Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can also lead to cancer and other diseases. To better understand how chromatin ...

Aging progressively affects how our bodies function. Among other effects, it reduces the ability of the hematopoietic system—the organs and tissues responsible for producing blood cells—to maintain ...