Centrioles and basal bodies (hereafter referred to as 'centrioles' for simplicity) are essential for the formation of cilia, flagella and centrosomes. Therefore, understanding the mechanisms governing ...

Tubulin superfamily members are essential for maintaining the microtubule cytoskeleton. α- and β-tubulin form the basic subunit of the microtubule polymer and assembly of microtubules is nucleated at ...

Centrioles are cylindrical structures involved in the generation of microtubules - fibers inside of cells that form a network to provide structure and shape to cells and to mediate transport processes ...

Biologists at the National University of Singapore (NUS) have uncovered how the protein NuSAP safeguards tiny structures inside cells called centrioles, revealing a mechanism linked to developmental ...

Mitosis is the process by which the genetic information encoded on chromosomes is equally distributed to two daughter cells, a fundamental feature of all life on earth. Scientists now examine how ...

A two-step recruitment model based on the findings for the CEP57-CEP63-CEP152 complex during a single cell cycle. (A) During S to G2 phase, CEP57 is gradually recruited to the procentriole, crucial ...

Centrioles are cylindrical structures involved in the generation of microtubules—fibers inside of cells that form a network to provide structure and shape to cells and to mediate transport processes.

Scientists say they have discovered critical features of cancer cells that may help clinicians better fight the disease. The researchers found that the number and size of centrioles are increased in ...

Human sperm cells are well-studied, so scientists were completely surprised to find a previously unknown structure in the little swimmers. And perhaps more surprising, this newfound structure may ...

Researchers have captured the assembly of the NLRP3 inflammasome inside intact human cells for the first time. These ...