The Horner--Wadsworth--Emmons (HWE) reaction is commonly used in organic chemistry to synthesize conjugated aldehydes. However, traditional HWE reaction methods sometimes have inconsistent (E)- and (Z ...
Methisazone is one of the most historically intriguing molecules in antiviral chemistry, an isatin-derived thiosemicarbazone ...
Scientists at the Institute of Science Tokyo (Science Tokyo) have successfully realized the highly selective asymmetric 1,6 addition of aliphatic Grignard reagents to α,β,γ,δ-unsaturated carbonyl ...
The Nature Index 2026 Research Leaders reveal the leading institutions and countries/territories in the natural sciences, health sciences, applied sciences and social sciences, according to their ...
CORRECTION: This story was updated on April 21, 2016, to clarify that the method described was not the first radical-based route to chiral quaternary carbon centers. The method is the first route ...
The Nature Index 2026 Research Leaders reveal the leading institutions and countries/territories in the natural sciences, health sciences, applied sciences and social sciences, according to their ...
The Horner–Wadsworth–Emmons (HWE) reaction is a fundamental reaction in organic chemistry, widely used to create conjugated carbonyl compounds. Conjugated carbonyl compounds are used in many ...
The Wadsworth–Emmons (HWE) reaction is a fundamental reaction in organic chemistry, widely used to create conjugated carbonyl compounds. Conjugated carbonyl compounds are used in many industries for ...
The reaction utilizes an iron catalyst together with an N-heterocyclic carbene (NHC) ligand, which suppresses unwanted side reactions to promote highly selective nucleophile addition. In organic ...
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