An important specialty in this field—and a signature area of study at the University at Albany's RNA Institute—is DNA nanotechnology, wherein the base pairs that comprise DNA molecules are manipulated ...

For stem cells to differentiate into the appropriate cell-type, transcription factors (TFs) must be tailored to highly specific expression patterns of lineage-specific genes. Abnormalities in the ...

A new technology allows scientists to map, in single cells, the DNA binding sites of transcription factors and other regulatory proteins that control gene activity, according to a study led by ...

Every cell in the body contains essentially the same DNA, yet a brain cell behaves differently from a muscle cell or an ...

DNA methylation is a key epigenome component that helps dictate how genes are expressed, contributing to normal cell and tissue differentiation during development, as well as the process of biological ...

Scheme showing the structure of cytosine, 5-methylcytosine, and 5-hydroxymethylcytosine. Adding a methyl group to the DNA base cytosine represses gene expression in mammalian cells. To remove the ...

This breakthrough transforms the building of synthetic DNA from a chemical process to an electrical one. Here’s what you’ll ...

When a wound does not heal properly, it leaves a scar. Similarly, mutations—which are permanent changes to genetic code—are ...

Hospital for Sick Children in Toronto researchers are reporting that targeted RNA sequencing can detect clinically actionable alterations in 87% of tumors and provide decisive findings where DNA-seq ...