Researchers have revealed the presence of a functional urea cycle in the star-shaped cells of the Alzheimer's Disease (AD) brain. Key results point to the role of the urea cycle in amyloid-beta plaque ...

Urea cycle disorders (UCDs) constitute a group of rare, inherited metabolic conditions arising from deficiencies in key enzymes of the urea cycle – the biochemical pathway responsible for converting ...

Targeted inhibition of an enzyme linked to the urea cycle called ornithine decarboxylase 1 (ODC1) in star-shaped cells in the brain called astrocytes, could prove beneficial in restoring memory ...

The National Urea Cycle Disorders Foundation (NUCDF), the leading patient advocacy group for people affected by urea cycle disorders (UCDs), today announced the launch of a two-year national project ...

The number of elderly suffering from Alzheimer’s Disease has been rapidly rising over the past decades. For a long time, scientists believed that misfolded aggregates of amyloid-beta protein ...