Ever bitten into a hot pie, yelped "Hothothot!" then had your taste buds go on strike for the next week? Taste buds are a ...

Bitter taste receptors, also known as TAS2Rs, are a distinct family of G protein-coupled receptors (GPCRs) originally recognised for their role in oral bitter taste perception. Recent research has ...

Receptor proteins, expressed on the cell surface or within the cell, bind to different signaling molecules, known as ligands, initiating cellular responses. Taste receptors, expressed in oral tissues, ...

Researchers at the University of North Carolina (UNC) at Chapel Hill School of Medicine have revealed the detailed structure of the bitter taste receptor, a protein called TAS2R14, and have shown ...

Bitter taste receptors inside cancer cells have been found to be activated in the presence of anti-cancer drugs. Shutting these receptors down could make the cells more susceptible to drug treatment ...

A bitter taste receptor, TAS2R14, has been shown to respond to both extracellular and intracellular signals. Indeed, it can respond to both signals simultaneously. This finding is especially ...