"This study characterizes a novel oral cancer tumor suppressor that drives immune surveillance but is inhibited by high levels of glutamine." BATF2 and how it helps with immunity BATF2 is a tumor ...

Researchers describe two enzymes newly identified for their roles in regulating macropinocytosis, a process cancer cells use to snatch extra nutrients from the jelly-like substance between cells. This ...

How does glutamine affect BATF2 and cancer cells? Many cancers are resistant to treatments that trigger the STING pathway. More recently, studies have shown that epigenetic changes – which turn genes ...

A Ludwig Cancer Research study has identified a complex chain of molecular chatter by which cancer cells, exploiting ordinary metabolic processes, program one set of noncancerous cells to manipulate ...

This article summarizes metabolic reprogramming in prostate cancer (PCa). Early PCa relies more on glycolysis.

Prostate cancer (PCa) is one of the most common malignant tumors among men worldwide. Following androgen deprivation therapy ...

Potent antitumor activity of the KRASG12D inhibitor MRTX1133 in pancreatic cancer: Augmenting the nanoparticle-paclitaxel chemotherapy response. This is an ASCO Meeting Abstract from the 2025 ASCO ...

Co-corresponding authors Jian Xu,PhD, (left) and Min Ni, PhD, (right) and co-first authors Junhua Lyu, PhD, (center left) and Yuannyu Zhang, PhD, (center right) identified and characterized a ...

(By Dr. Mandeep Singh Malhotra) Cancer still remains a prominent cause of mortality across the globe. Despite recent breakthroughs in the treatment strategies, the understanding of how cancer begins ...