Hydroxyurea remains effective over the long term among children with sickle cell disease, real-world data suggested. The average time on hydroxyurea was 5 years, with many children on the therapy for ...

Hydroxyurea is generally contraindicated in patients with sickle cell disease who become or plan to become pregnant, but post-marketing safety data suggest that treatment continuation is safe. The ...

Taking the sickle cell drug hydroxyurea during or shortly before pregnancy does not appear to cause specific issues in newborns, according to the first prospective study of pregnancies involving ...

Hydroxyurea is an oral chemotherapy drug that doctors may prescribe to people with sickle cell disease. It may help prevent complications due to sickle-shaped blood cells clumping together in small ...

Taking the sickle cell drug hydroxyurea during or shortly before pregnancy does not appear to cause specific issues in newborns, according to the first prospective study of pregnancies involving ...

(WASHINGTON, April 17, 2024) — Hydroxyurea remains effective long-term in reducing emergency department visits and hospital days for children living with sickle cell disease (SCD), according to new ...

Researchers have revealed that hydroxyurea significantly reduces infections in children with sickle cell anemia. Their findings enhance strong evidence of hydroxyurea's effectiveness and could ...

SAN DIEGO -- Treatment with hydroxyurea led to more hematologic dose-limiting toxicities (DLTs) compared with placebo in patients with hemoglobin SC, a milder form of sickle cell disease (SCD), a ...

Researchers have identified an alternate method to study changes during the DNA replication process in lab settings using genetically modified yeast. The new approach offers a clearer window than ...

Hydroxyurea, a myelosuppressive agent that has been a standard treatment in sickle cell disease (SCD) for decades, remains effective over the long term in children with the disease, according to a ...