When we think about iron imbalance, most people are familiar with iron deficiency and the health problems it can cause. What ...

Expert Rev Mol Diagn. 2010;10(6):755-763. The diagnosis is based on a three-step strategy. The first step is recognizing clinical signs and symptoms. Many symptoms in various combinations may suggest ...

Hemochromatosis is a disorder that causes your body to absorb too much iron. Blood tests that measure iron levels in your blood and liver can help diagnose the condition. The medical disorder ...

Iron overload is prevalent among adults with sickle cell disease (SCD), according to a study presented at the annual meeting of the American Society of Hematology, held from Dec. 6 to 9 in Orlando, ...

People from the Outer Hebrides and north-west Ireland have the highest risk of developing a genetic disease that causes a dangerous build-up of iron in the body, a study suggests. The study marks the ...

Iron metabolism imbalance and ferroptosis are central to PF pathogenesis, offering new therapeutic targets. Ferroptosis links oxidative stress, iron overload, and fibrotic remodeling, affecting key ...

Saturation of TfR1 leads to the dissociation of Hfe and the binding of the alter to the TfR2, which in turn influences the binding of BMP6 to its receptors on the membrane. Increased liver iron ...

A case report highlights pulmonary siderosis in a welder with progressive dyspnea and recurrent infections, underscoring occupational history, possible systemic iron overload, and the need to monitor ...

Sometimes, people with mild thalassemia may be told to supplement with iron. Iron supplements are only appropriate for certain types of thalassemia, though, and can be dangerous for people with more ...

BERLIN—Kidney transplant recipients who have iron overload are at increased risk for bacterial infection compared with those who have normal iron levels, according to preliminary results of a Spanish ...

Although the majority of genetic iron-overload syndromes have now probably been identified, several paths of investigation remain open. First, clinical experience strongly indicates that some ...