A new HIC–MS method using ammonium tartrate improves ADC characterization, enabling efficient drug-to-antibody ratio analysis without complex workflows. A proteomics workflow combining laser ablation ...

MOBILion Systems demonstrated that high-resolution ion mobility in its PAMAF mode overcame LC-MS inefficiencies, enabling ...

Relationship between immune-inflammatory markers and clinical features and deepness of tumor response and prognosis of patients with PD-L1 ≥50% metastatic NSCLC receiving first-line immunotherapy.

Blood is an ideal, minimally invasive sample for biomarker discovery, but its complexity might make untargeted, deep proteomics challenging. This work compares plasma proteomics approaches using both ...

Native Capillary Electrophoresis–Mass Spectrometry Enables Quantitative Profiling of Endogenous Protein Complexes ...

The sample throughput of high-sensitivity liquid chromatography-mass spectrometry (LC-MS) based proteomics analysis is restricted by the pressure limitations of LC and column hardware, with some ...

To identify specific chemicals or molecules in the life sciences and medical research, scientists often use mass spectrometry (MS), usually paired with liquid chromatography (LC). These technologies ...

High-performance liquid chromatography-mass spectrometry (HPLC-MS) combines the separation power of LC with the detection specificity of MS. It has become an indispensable analytical tool in the ...