Using localized force-distance curves from AFM, a deep neural network was trained and biologically validated to predict and accurately distinguish macrophage polarization states, including complex ...

To investigate their recruitment, Gata6-iCreER mice were crossed with Cd45-Dre and R26-tdT mice, enabling specific lineage tracing of cavity macrophages. Flow cytometry and immunofluorescence ...

Objective Macrophages and kidney cell pyroptosis/ferroptosis could play an important role in the pathogenesis of lupus ...

Recombinant Hirudin (rH) inhibited the polarization of M2-type macrophages and protease-activated receptor-1 (PAR-1) in diffuse large B-cell lymphoma (DLBCL). A study of 32 clinical samples from ...

After five decades of use, flow cytometry is entrenched in biomedical science. Besides enabling the quick processing of cells in suspension, flow cytometry provides quantitative results across ...

Around the same time, Mack Fulwyler, an engineer working at Los Alamos National Laboratory, needed to separate particles, so he drew on existing techniques to create droplets to separate cells from a ...

Combining a serum-free medium with a xeno-free serum replacement creates a reliable system for generating functional dendritic cells and macrophages. Myeloid cells such as dendritic cells and ...

Flow cytometry is an invaluable method for biomedical research. Since its development over 50 years ago, technology for flow cytometry has progressed rapidly, allowing for the detection of more and ...

A recent study has demonstrated the power of metabolic engineering in enhancing the antitumor activity of chimeric antigen ...

Researchers developed and validated a label-free, non-invasive method combining AFM with deep learning for accurate profiling of human macrophage mechanophenotypes and rapid identification of their ...