Chromosome translocations are relatively common in humans. They result from the exchange between nonhomologous autosomes. Approximately one couple out of 600 carries a reciprocal translocation [1].

Meiotic recombination assures genetic variation during breeding. During meiotic prophase I, chromosomes are organized in a loop-base array by a proteinaceous structure called meiotic chromosome axis ...

DSBs are more likely to occur in some genomic regions than others. Elucidating mechanisms shaping the DSB “landscape” requires identifying the biochemical factors involved, understanding how they ...

The exchange of DNA between chromosomes during the early formation of sperm and egg cells normally is limited to assure fertility. But when there are too many of these genetic exchanges, called ...

During sexual reproduction, haploid gametes (i.e. eggs and sperm) are generated from diploid precursors through the specialized cell division of meiosis. Meiosis reduces ploidy by following one round ...

Germination of teliospores on complex medium containing thiabendazole (TBZ) or botran and TBZ gave 0.3%-7.0% colonies with diploid sporidia. Diploid sporidia heterozygous for complementing, closely ...

Random segregation leads to each of parent’s alleles having an equal chance (0.5 probability) of being passed down. This can be visualized in a traditional Punnett square (left), which leads to a 3:1 ...

Anyone who studies biology at school or college will learn that haploid gametes produced from a diploid cell will each contain just one of the two copies of a gene inherited from mother and father.

Research on so-called selfish genetic loci is providing scientists with greater insight into the biology of chromosome segregation and inheritance. A series of rodent experiments showed that even with ...