Nature

Detection and calibration of microdeletions and microduplications by array-based comparative genomic hybridization and its applicability to clinical genetic testing

Purpose: Genome-wide telomere screening by fluorescence in situ hybridization (FISH) has revealed that ≈ 6% of unexplained mental retardation is due to submicroscopic telomere imbalances. However, the ...
ascopubs.org

Predictive Role of Interphase Cytogenetics for Survival of Patients With Multiple Myeloma

PURPOSE: Recent metaphase cytogenetic studies suggested that specific chromosomal abnormalities are of prognostic significance in patients with multiple myeloma (MM). Because the true incidence of ...
Nature

Section E6.1–6.4 of the ACMG technical standards and guidelines: chromosome studies of neoplastic blood and bone marrow–acquired chromosomal abnormalities

Disclaimer: These American College of Medical Genetics and Genomics standards and guidelines are developed primarily as an educational resource for clinical laboratory geneticists to help them provide ...
JSTOR Daily

Contrast between the Environmental pH Dependencies of Prophasing and Nuclear Membrane Formation in Interphase-Metaphase Cells

This is a preview. Log in through your library . Abstract In Chinese hamster Don cells, fusion of an interphase cell with a metaphase cell resulted either in prophasing of the interphase nucleus, ...