Fluorescent probing of mitochondrial membrane potential (ΔΨm) has emerged as an indispensable tool for interrogating mitochondrial function and tracking the early stages of apoptosis. Lipophilic ...
A new study published in Engineering has uncovered a regulatory mechanism linking lysosomal function to mitochondrial ...
Researchers in Oslo and Athens report that the small molecule phenazine methosulfate functions as a chemical “redox bypass”, ...
Scientists discover an unexpected involvement of sodium transport in mitochondrial energy generation
The GENOXPHOS (Functional Genetics of the Oxidative Phosphorylation System) group at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has discovered a crucial role of sodium in the ...
A Parkinsonian mystery—how PINK1 locks onto malfunctioning mitochondria—now has a structural solution. Researchers at the University of Melbourne led by Sylvie Callegari, Alisa Glukhova, and David ...
A new study published in Nature Communications has uncovered a communication pathway between mitochondria and RNA granules ...
(1) Mitochondrial failure, where aging reduces compensatory mtDNA replication, leads to ROS accumulation, respiratory chain damage (NADH/CoQ deficiency), and membrane potential collapse. These defects ...
Mitochondria are cell organelles surrounded by a double membrane. In addition to numerous essential functions in the metabolism of the cell, they also play a key role in the integration of signals ...
Jesús Vázquez Cobos, Iván López-Montero, Enrique Calvo Alcocer, Pablo Hernansanz Agustín, Carmen Morales Vidal, José Antonio Enríquez, Rebeca Acín Pérez, Sara Jaroszewicz and José Luis Cabrera Alarcón ...
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