DNA methylation is highly dynamic during mammalian embryogenesis. It is broadly accepted that the paternal genome is actively depleted of 5-methylcytosine at fertilization, followed by passive loss ...
Philosophical Transactions: Biological Sciences, Vol. 358, No. 1436, Epigenesis versus Preformation during Mammalian Development (Aug. 29, 2003), pp. 1403-1409 (7 pages) Epigenetic asymmetry between ...
Using human eggs in the quest to make donor-specific embryonic stem cells is controversial. A method developed in mice, if applicable to humans, could eliminate the need to obtain eggs for this ...
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