A novel cell therapy approach using cord blood-derived natural killer (NK) cells pre-complexed with AFM13, or acimtamig, a CD30/CD16A bispecific antibody, was safe and generated strong response rates ...
Flow cytometry is a strong analytical method that is utilized to determine, measure, and examine cells and particles in a heterogeneous mixture. The standard instrument comprises three primary ...
Around the same time, Mack Fulwyler, an engineer working at Los Alamos National Laboratory, needed to separate particles, so he drew on existing techniques to create droplets to separate cells from a ...
Flow cytometry offers practical advantages for real-time monitoring of CAR T cell expansion, persistence, and toxicity risk in aggressive large B-cell lymphoma patients. Early CAR T cell expansion is ...
Flow cytometry is a single-cell analytical technique that uses fluorophore-labeled cell structures or biomarkers to differentiate between cell populations. Through this method, researchers detect the ...
CD19 CAR-NK cell therapy with rituximab achieved durable complete responses in Waldenström Non-Hodgkin lymphoma, with up to 15 months of remission. The QUILT-106 study reported 100% disease control ...
CAR has the ability to specifically recognize target cells and activate NK cells to kill tumor cells. Therefore, the design and engineering of the CAR structure are crucial for CAR-NK therapeutic ...