In its effort to correlate genomic structure with gene function, the 4D Nucleome Consortium (4DN), led by Job Dekker, Ph.D., ...

Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published in Nature. Chromosomes are thread-like structures that carry a cell's ...

An illustration of multicolored tangle of threads within a small black sphere. A 3D illustration shows DNA packaged into the nucleus, scientists with the 4D Nucleome project are now building accurate ...

In a landmark effort to understand how the physical structure of our DNA influences human biology, Northwestern investigators and the 4D Nucleome Project have unveiled the most detailed maps to date ...

Reconstructed particle-on-a-string 3D genomes of Brassica rapa. (a) 3D organization with expanded views of the separate chromosome territories. (b) Spatial distribution of telomeres and centromeres of ...

New research from the Wisconsin Institute for Discovery is tackling a complex packing problem. Thanks to the development of a powerful new computational tool introduced in a study published in the ...