The patient had porphyria cutanea tarda (PCT), a cutaneous disease that results from alteration in the pathway of heme synthesis. Three types of PCT are recognized. Types 1 and 2, which account for ...

One patient, a 39-year-old woman, went to a dermatologist seeking care for fluid-filled blisters over the backs of her hands and arms. Another patient, a 56-year-old man, sought care from his general ...

Variegate porphyria (VP) is an autosomal dominant condition that results from the deficiency of protoporphyrinogen oxidase (PPOX, EC 1.3). The build-up of porphyrin precursors delta-aminolevulinic ...

Porphyria refers to a group of genetic disorders that can affect the nervous system or the skin. Share on Pinterest All types of porphyria are characterized by a slower than normal production of heme.

After 108 weeks of continuous Imatinib therapy, the patient noted the appearance of the same painful blisters on her hands, feet and legs. The uroporphyrin level was 64.9% (normal <20%), with total ...