Therapeutic landscape of Rad51 in cancer treatment. Key elements include (1) DNA damage sources (PARPi, chemo/radiotherapy);(2) repair pathways (Rad51‐mediated HR); (3) intervention strategies (Rad51 ...
Different genomic alterations in DNA damage repair (DDR) pathways occur in 20% to 25% of advanced prostate cancer, including ...
The small ring-like structures visible in the magnified area represent the RAD51 protein, which has adopted a non-functional shape as a result of its interaction with Apt1. The research study has been ...
A research group at the Italian Institute of Technology (IIT-Istituto Italiano di Tecnologia) has identified a candidate molecule that could improve current therapies against pancreatic cancer. The ...