Researchers at The University of Texas MD Anderson Cancer Center have identified a key enzyme - RNase H2 - that helps triple-negative breast cancer (TNBC) cells survive high levels of DNA replication ...
Next generation sequencing reveals targetable mutations in multiple sarcoma histologies. This is an ASCO Meeting Abstract from the 2023 ASCO Annual Meeting I. This abstract does not include a full ...
Two research teams led by Professors Brian Luke and Helle Ulrich at the Institute of Molecular Biology have deciphered how two enzymes, RNase H2 and RNase H1, are coordinated to remove RNA-DNA hybrid ...
Many breast cancer therapies work by causing DNA replication stress, but triple-negative breast cancer (TNBC) cells survive this stress, even at high levels TNBC cells overexpress an enzyme, RNase H2, ...
Previous work showed that RNase H2 activity helps triple-negative breast cancer (TNBC) cells manage high levels of replication stress, offering new therapeutic insights. Researchers from The ...
Ribonucleotides are frequently misincorporated into DNA during replication, arising from imperfect sugar discrimination by DNA polymerases and high intracellular ribonucleotide triphosphate pools.
Two research teams led by Professors Brian Luke and Helle Ulrich at the Institute of Molecular Biology have deciphered how two enzymes, RNase H2 and RNase H1, are coordinated to remove RNA-DNA hybrid ...
Scientists have deciphered how two enzymes, RNase H2 and RNase H1, are coordinated to remove RNA-DNA hybrid structures from chromosomes. Two research teams led by Professors Brian Luke and Helle ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results