Why retinoic acid is effective in this setting but not against primary tumors, has been speculated about for nearly 50 years. Scientists resolved the mystery, showing the drug 'hijacks' a normal ...

A vitamin A byproduct has been found to quietly disarm the immune system, allowing tumors to evade attack and weakening cancer vaccines. Scientists have now developed a drug that shuts down this ...

Scientists at the Princeton University Branch of the Ludwig Institute for Cancer Research have identified novel mechanisms by which a metabolic derivative of vitamin A—all-trans retinoic ...

Monocytes, macrophages, and myeloid dendritic cells are central to the host response to cancer, and generally not in a good way. 1,2 Tumor-associated macrophages, often the most abundant cells in ...

Gemtuzumab Ozogamicin Improves Event-Free Survival and Reduces Relapse in Pediatric KMT2A-Rearranged AML: Results From the Phase III Children's Oncology Group Trial AAML0531 Arsenic combined with ...

Human pluripotent stem cells (hPSCs), when exposed to the right molecular signals in the right order, can become any cell type in the human body. Regenerative medicine seeks to derive blood-forming ...