Figure 1: CLASP1/2 depletion causes the formation of multipolar spindles. Figure 3: Loss of spindle-pole integrity in the absence of CLASPs is preceded by the presence of misaligned chromosomes with ...

Scientists have gained new insight into the formation of the spindle, which is the molecular machine that divides up genetic material prior to cell division. Their work focuses on the motor protein, ...

The mitotic spindle, an apparatus that segregates chromosomes during cell division, may be more complex than the standard textbook picture suggests. The mitotic spindle, an apparatus that segregates ...

This is a preview. Log in through your library . Abstract Spindle formation in fission yeast occurs by the interdigitation of two microtubule arrays extending from duplicated spindle pole bodies which ...

Robert Blackwell, Christopher Edelmaier, Oliver Sweezy-Schindler, Adam Lamson, Zachary Gergely, Eileen O’Toole, Ammon Crapo, Loren Hough, J. Richard McIntosh ...

In 2000, researchers discovered that mutations that inactivate a gene known as TRIM37 causes a developmental disease called Mulibrey nanism. The extremely rare inherited disorder leads to growth ...

Cambridge, Mass. - April 26, 2012 - The mitotic spindle, an apparatus that segregates chromosomes during cell division, may be more complex than the standard textbook picture suggests, according to ...