Imagine your immune cells could be modified to attack any kind of cancer. T cell receptor (TCR) therapy has the potential to one day become a universal cancer treatment. But there are risks.

Every time our body encounters a new disease-causing agent, a crucial defense system called adaptive immunity comes into play. T cells, the top agents in this system, survey the internal environment ...

One of the most exciting advances in cancer treatments in the past decade is the development of T cell immunotherapies, in which a patient's own immune system is trained to recognize and attack ...

A new AI tool that models how variations in peptides change T cell receptor binding could help design immunotherapies with fewer off-target effects. Protein complexes that adorn the surface of T cells ...

A new multi-pronged antibody design could help immune cells receive stronger activation signals against cancer. Researchers at the University of Southampton have identified a new strategy that could ...

Scientists at École Polytechnique Fédérale Lausanne (EPFL), and at UNIL-CHUV, University Hospital Lausanne (CHUV) and University of Lausanne (UNIL) have developed a computational method to create ...

UT Southwestern Medical Center researchers have discovered that increasing the levels of a protein called BACH2 makes ...

The gray portion of this schematic represents a nanodisc, where for the first time researchers were able to replicate the native membrane environment (red dots) of a T-cell receptor (cyan). One of the ...