This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

A 36-year-old man who was undergoing long-term hemodialysis was hospitalized with a two-day history of increasing dyspnea on exertion. He stated that he did not have cough, orthopnea, or night sweats.

A 67-year-old white female who was treated for exacerbation of her chronic obstructive pulmonary disease returned a week later with the same shortness of breath. This time she had new-onset bilateral ...

Gathering of initial clinical data guided by the differential diagnosis can orient care by identifying patients in need of urgent evaluation and by highlighting possible etiologies. The initial ...

Pleural effusions complicate up to 57% of bacterial pneumonias. They vary in severity, ranging from uncomplicated effusions to empyema. Some require only antibiotics and observation, while others ...

A 50-year-old woman presented with a short history of loss of weight and appetite, constipation, right-sided abdominal pain, unsteady gait and headache. Physical examination revealed a soft nontender ...