Oct 23, 2020 · BV-2 Microglial Cells, derived from C57/BL6 mice and immortalized with v-raf/v-myc, model primary microglia in neurodegenerative disease research. The BV-2 cell line is an …

BV2 is a mouse derived microglial cell line broadly used in neuroscience research. This immortalized cell line can serve as an in vitro model to study neurodegenerative diseases and …

Here, we re-evaluated strengths and potential short-comings of BV-2 cells. Their response to lipopolysaccharide was compared with the response of microglia in vitro and in vivo.

Apr 29, 2025 · BV2 cells, an immortalized murine microglial cell line, offer a widely used alternative for investigating neuroinflammatory mechanisms. Their reproducibility and ease of …

Genome-wide inspection of chromosomal aberrations in microglia BV-2 cells by array-based comparative genomic hybridization. The suitability of BV2 cells as alternative model system for …

Quickly thaw by rapid agitation in a 37°C water bath within 45-90 seconds. The water bath should have clean water containing an antimicrobial agent. As soon as the sample has thawed, …

Sep 27, 2023 · BV2 microglia are a v-raf/v-myc-immortalised murine cell line [1] commonly used in in vitro studies of microglia. They can be stimulated into a reactive, inflammatory phenotype …

The BV-2 cell line is defined as an oncogene transformed immortalized microglial cell line commonly used in in vitro studies to investigate microglial phenotype and function within the …

These results suggest that BV2 microglia activated by LPS triggered TLR4/MyD88/NF-κB signaling pathway that induced the release of IL-1β and could participate in the PC12 cells injury.

BV2 cell line is a mouse microglial cell line, which are derived from the brain tissue of C57/BL6 mice and immortalized using the J2 retrovirus. The cells are commonly used as a model for …