GLP-1 agonists are a class of medications that mainly help manage blood sugar (glucose) levels in people with Type 2 diabetes. Some GLP-1 agonists can also help treat obesity.

In accordance with the expression of GLP-1 receptor on brainstem and hypothalamus, GLP-1 has been shown to promote satiety and thereby reduce food and water intake.

If you're just starting to learn about GLP-1s or are considering them as part of your treatment plan, we’ll go over what you need to know. We’ll explain their benefits, how they work, potential side effects and …

May 21, 2025 · In this McKinsey Explainer, we look into what are GLP-1 medications and explore how they work, side effects, and more.

Apr 14, 2025 · Learn how GLP-1 drugs work for diabetes and weight loss. Explore GLP-1 benefits, side effects, and emerging research on these medications.

Oct 27, 2025 · GLP-1 agonist drugs treat diabetes by balancing blood glucose levels. Here’s our list of GLP-1 agonists, how they work, similarities and differences, and more.

Dec 31, 2025 · GLP-1 RAs first emerged as type 2 diabetes medications, to be prescribed as an adjunct to diet and exercise. Exenatide (Byetta, AstraZeneca) was the first FDA-approved GLP-1 RA in 2005.

Glucagon (GCG) like peptide 1 (GLP-1) has emerged as a powerful player in regulating metabolism and a promising therapeutic target for various chronic diseases. This review delves into the physiological …

Aug 18, 2025 · GLP-1 agonists, also known as GLP-1 receptor agonists, are a class of medications designed to mimic the effects of glucagon-like peptide 1 (GLP-1), a hormone naturally produced in …

Jul 14, 2025 · Glucagon-like peptide-1 (GLP-1) receptor agonists (semaglutide [Wegovy, Ozempic, Rybelsus]) and dual incretin agonists (tirzepatide [Zepbound, Mounjaro]) are medications that reduce …