Harmane, or harman, also known as 1-methyl-β-carboline, is a heterocyclic amine and β-carboline found in a variety of foods including coffee, [1] sauces, [2] and cooked meat. [3]

May 7, 2024 · Harmane’s presence in magic mushrooms has been of particular interest to researchers due to its potential contribution to the psychedelic experience. This guide details harmane’s most …

Jul 13, 2017 · Essential tremor prevention includes avoiding harmane-containing foods and supporting our bodies’ detox systems with healthy foods, such as by eating a primarily plant-based diet high in …

Jul 11, 2014 · The highest levels are found in those who have both essential tremor and cancer—suggesting harmane may be playing a role in both diseases. And the higher the harmane …

Harmane is a known tremorigenic β-carboline (a type of heterocyclic amine) found in cooked meat, roasted coffee beans, and tobacco. Thus, this compound represents a potentially important exposure.

Harmane inhibits the I1 imidazoline receptor (IC50 = 30 nM) to reduce blood pressure and has antidepressant, anti-anxiety, anticonvulsant, and analgesic effects.

Nov 5, 2025 · Discover what foods contain harmane, a neuroactive compound found in cooked meats, coffee, and sauces. Learn about its dietary sources and potential health effects.

Mar 2, 2025 · In this study, the focus was on elucidating the antibacterial effect and mechanism of harmane against E. coli O157:H7. In addition, the effectiveness of harmane on the preservation of …

Harmane is related to other alkaloids, harmine and harmaline, first isolated in the 1840s from the seeds of the plant Peganum harmala. [5] The name derives from the Arabic word for the plant,...

Jan 1, 2013 · Harmane is a potent, tremor-producing β-carboline alkaloid and is used in epidemiological studies. It is one of the most abundant of all dietary heterocyclic amines, and human exposure to …