Leptomeningeal Disease: What It Is, Symptoms & Prognosis
Leptomeningeal disease (also known as LMD, leptomeningeal metastases, or LM) is cancer in your cerebrospinal fluid and in your leptomeninges, the membranes that surround your brain …
Leptomeningeal Disease | Neuro-Oncology Program | UPMC …
Leptomeningeal Disease (LMD) happens when cancer cells invade the fluid and protective membranes surround the brain and spinal cord. Learn more from UPMC.
Leptomeningeal Disease: Current Approaches and Future Directions
Leptomeningeal disease (LMD), or spread of cancer cells into the pia and arachnoid membranes encasing the brain and spinal cord, is associated with high symptom burden and poor survival …
Leptomeningeal Cancer Symptoms, Treatment and Prognosis
Leptomeningeal disease (LMD), also known as leptomeningeal carcinomatosis, is a condition where cancer spreads to the brain, spinal fluid and leptomeninges, the thin layers of tissue …
Leptomeningeal Metastasis - AIM at Melanoma Foundation
Leptomeningeal metastasis—also called leptomeningeal carcinomatosis, leptomeningeal disease, or simply “LMD”—is the spread of cancer to a particular part of the brain called the …
Leptomeningeal metastatic disease: new frontiers and future …
Dec 9, 2024 · In this Review, a multidisciplinary group of experts describe the emerging evidence and areas of active investigation in LMD and provide directed recommendations for future …
Leptomeningeal Disease, CNS Metastasis | Moffitt
Leptomeningeal disease (LMD) is a rare form of central nervous system (CNS) metastasis that occurs when cancerous cells spread to the leptomeninges—the delicate layers of tissue that …
Clinical features and diagnosis of leptomeningeal disease ... - UpToDate
Jul 14, 2025 · Leptomeningeal disease (LMD; also referred to as leptomeningeal metastases or carcinomatous meningitis) is a rare but frequently devastating complication of advanced …
New hope for leptomeningeal disease care - MD Anderson Cancer Center
Apr 3, 2017 · When cancer spreads to the cerebrospinal fluid surround the brain and spinal cord and/or the lining of the brain and spinal cord, it causes an aggressive disease called …
Leptomeningeal metastatic disease: new frontiers and future
In this Review, a multidisciplinary group of experts describe the emerging evidence and areas of active investigation in LMD and provide directed recommendations for future research.