When red blood cells reach the end of their lifespan, they are removed by the spleen and liver. Inside these organs, specialized cells break down the old red cells and release their components. The iron inside hemoglobin is carefully preserved. The liver collects this iron and binds it to proteins that keep it safe and transportable. One of the main proteins involved is transferrin, which carries iron through the bloodstream to tissues that need it. Some of the iron is stored inside liver cells
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