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4:04
⭐️ Update on longer outcomes with ribociclib (Kisqali) and abemaciclib (Verzenio) in hormone receptor positive/HER2 negative early stage breast cancer. ⭐️ These are CDK 4/6 inhibitors given in conjunction with endocrine therapy to reduce risk of recurrence. (CDK 4/6 inhibitors are standard of care in the treatment HR metastatic breast cancer as well). In early stage BC, abemaciclib is taken for 2 years and ribociclib for 3 years. In this video, I share with you recent updates (they are positive!
38K views
Oct 8, 2025
Facebook
Eleonora Teplinsky, MD
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STUDY ^ Side effects from abemaciclib (Verzenio) lower with gradual dose increase #breastcancer
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Kisqali for breast cancer treatment is expensive. Ask about the Novartis Patient Support Program!
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🚨 Today, the FDA approved #ribociclib (Kisqali) in combination with an aromatase inhibitor for the adjuvant treatment of adults with hormone receptor-positive (HR ), HER2-negative (HER2–) stage II and III early breast cancer at high risk of recurrence. High risk was defined as lymph node positive disease or if lymph node negative, patients either had to have grade 3 or grade 2 AND Ki67>= 20% or high genomic risk (based on assays like Oncotype or mammaprint). Kisqali was given 400 mg daily (*it’
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A Washington high school cross-country runner is at the center of a growing debate over transgender athletes in girls’ sports. Logan Mihailoff competed in the boys’ division earlier this season, finishing 76th at the Ultimook Race. Weeks later, Mihailoff competed in the girls’ division, finishing 2nd out of 195 runners at the Nike Portland XC Invitational before winning a girls’ varsity race against Union. The results have sparked major backlash online, while the Camas School District says it is
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Master & Will get heated over VAR decisions in Argentina's win over Egypt 😡 For more content from The S* Word, follow us and Subscribe to our YouTube channel by clicking the link in our bio 18 only. Restrictions and eligibility requirements apply. Event contract trading involves risk and may not be suitable for all investors. Prices, values, and available markets may differ from those mentioned. For more information see kalshi.com/regulatory. @kalshi @kalshisports @foxsoccer #fyp #fifaworldcup
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The Trump administration has urged its trans service members to voluntarily quit by March 26th - this comes after a memo filed by the Pentagon last Wednesday, stating that transgender service members will be removed from the military unless granted a waiver. A memorandum from the Department of the Air Force, dated March 1, was submitted on Sunday to the U.S. District Court for the District of Columbia as part of the case Talbott v. Trump, a lawsuit filed by GLAD Law and the National Center for L
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I thought the hard part would be getting through chemo, surgery, and radiation. I thought once the cancer was removed, I'd finally be done. For some of us, that's not how it works. Because my cancer is hormone receptor-positive, was found in my lymph nodes, and there was still residual cancer present after surgery, my team is recommending additional treatments to help lower my risk of recurrence. My next chapter includes: • Zoladex to shut down my ovaries and reduce estrogen production. • Letroz
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