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Chopper
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How COVID-19 Enters Your Cells (Simple Explanation)
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Johannes Kepler Universität Linz
@biochemistry_nutrition_medlab on Instagram: "Vestibulocochlear pathway.🧠SARS-CoV-2 primarily enters the body through the ACE2 in the respiratory epithelium.The virus is replicated & enters the circulation by attaching to the β chain of hemoglobin in erythrocytes, & transported and binds to several organs.ACE2 receptors are abundant in neurons & glial cells of various brain regions like the cortex,striatum,substantia nigra,& the brainstem,suggesting the neuronal damage potential of SARS-CoV- 2
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In this lecture, Dr. Been dives into research examining how the SARS-CoV-2 spike protein can drive platelet activation and blood clot formation through several mechanisms—including ACE2 suppression, integrin interaction, complement system activation, and direct platelet signaling. What’s Covered: -How spike protein disrupts ACE2 and causes overactivation of the Ang II / AT1R pathway -The role of integrin αvβ3 and MAPK signaling in activating platelets -Activation of the complement system (C3a, C
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🧬 When immunoglobulin Y (IgY)—a type of antibody produced by chickens—binds to the SARS-CoV-2 spike protein, it acts as a neutralizing agent that blocks the virus from entering host cells. Because IgY is derived from immunized egg yolks and used in, for example, nasal or oral sprays, it targets the virus at the mucosal surface before it can establish a deep infection. 🧬What Happens Upon Binding: Blocks ACE2 Receptor Binding: IgY binds specifically to the Receptor-Binding Domain (RBD) or S1 sub
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